LoRa E5 UART Bootloader

Is it possible to program an E5 Mini Dev Board via UART (using STM32CubeProgrammer) - doesn’t look like it from my initial attempts. If not out of the box, has anyone in the community attempted to write a UART bootloader?

This would allow much more convienient programming via USB rather than requiring an external STLINK.

Is possible but Seeed made a mess. USART1 boot requires PA10 and PA9 guess what they connected to the CP2102, PB6 and PB7 what were they thinking? So you can connect the USART1 or USART2 pins to the CP2102. And trigger the boot loader by the option bytes or programmatically.