this is something in windows i think, it happens to me all the time, i have never had arduino ide reject a setup, other than if you try to upload to the wrong board the code may not work, the only solution i have found is to make sure you already have the correct board selected in the IDE before you first connect the usb, also if you delete the unused boards from the config file that may help… I have no idea how it knows what wrong board to select, but i think windows saves the config by serial number of the device, you can try google for reset com port numbering and try that
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