Some progress made with the use of python virtual environments:
pi@iotpi:~/venvs/test $ grove_led 5 Check whether I2C enabled and Grove Base Hat RPi or Grove Base Hat RPi Zero inserted pi@iotpi:~/venvs/test $ source venv/bin/activate (venv) pi@iotpi:~/venvs/test $ grove_led 5 # proceeds to run & lights work
Running from a file still fails. Will continue investigation :).