@Arvid_Blaser: Maybe current goes into usb-voltage regulator? If you say that LoRa-E5 works fine on other host board, maybe could be a problem in host board and not in LoRa module.
My configuration is LoRa-E5+MSP430F5340 with direct 3.3V power supply. Current consumption of whole thing should be couple of uA in sleep mode, but there was weird thing going on in UART bus which get me 70uA in sleep mode. When added pull up to UART bus, current consumption is couple of uA. This solution is quite weird. Since I know, UART shouldn’t need pull-up’s.